Research chair OPSYRII
Funding: INCa (French national cancer institute), in partnership with the Université de Lille, the SCALab UMR 9193 laboratory, the Centre Oscar Lambret and the ONCOLille Institute.
Recipient: Kristopher Lamore
This research chair aims to develop a program to improve the support provided to cancer patients and their families through the development and evaluation of interventions.
What is a research chair?
The purpose of a chair is to strengthen a research team to develop a priority research theme. To this end, financial and human resources are made available to the chairholder to enable him or her to develop projects with a strong economic and social impact, as well as to develop research, teaching, and training. This allows the development, consolidation and structuring of interactions between the academic and the socio-economic environment.
What are the objectives of the opsyrii research chair?
The general objective is to develop a research program aimed at increasing and disseminating knowledge about the adjustment processes of patients, their families, and healthcare professionals. To this end, innovative interventions will be designed and evaluated to test their effectiveness with a goal of optimizing the support offered to patients and their care pathways.
Over the last ten years, research in psycho-oncology has focused mainly on the psychological repercussions of cancer on patients and their life partners. This research has made it possible, among other things, to identify the coping strategies used by these people to cope with the disease. In addition to the couple, the family is also strongly impacted after a cancer diagnosis in one of its members. It is precisely these family interactions in cancer care that have been less explored, and yet suggest that family members can and should be better supported in this ordeal.
1. The ICEbreaker intervention: Information, communication, and emotion regulation in cancer care
2. RESIST: The announcement of the cancer progression: a communication challenge between healthcare professionals and the patient-family dyad
3. The TRANSITION intervention: Accompanying pediatric cancer survivors and their parents in the transition from pediatric to adult healthcare
See the Chair's website for more information (available from 04/10/2022)
LOLEMATH (INSPE Amiens)
Funding : PIA - Pôle Pilote 100% IDT - INSPÉ de l’Académie d’Amiens – Hauts-de-France
Lolemath : Partnership scheme aimed at improving the capacities of pupils (from cycle 1 to 3) in language (speaking and reading) and in mathematics.
Coordinator: Sandrine Mejias
Funding: INCA (Institut National Contre le Cancer)
Coordinator: Delphine Grynberg & Guillaume Piessen (CHU de Lille)
Most esogastric (EG) cancer patients will undergo surgery. Unfortunately, despite recent medical improvements, severe post-operative morbidity is 30% and the 90-day post-operative mortality rate is about 13%. Many studies have identified medical and tumor factors predicting morbidity and mortality in these patients. However, no study has yet evaluated their role of depressive and/or anxious symptoms in the poor prognosis in EG cancer patients despite evidence of an association between these symptoms and morbimortality after cardiac surgery. Concerning the explanatory mechanisms, these affective symptoms may lead to disrupted immunological and inflammatory responses, which could account for the poor prognosis after surgery. Surprisingly, no study has yet tested this hypothesis in any surgical populations, ignoring the role of depressive and/or anxious symptoms and the associated disrupted biological responses in morbimortality after surgery. However, this issue is very relevant in EG cancer because these symptoms affect 30% of patients, making them highly vulnerable to post-operative morbimortality.
Project objectives and methodology
Using the FREGAT national clinico-biological database, which prospectively collects clinical, biological and psychological data from EG cancer patients at the main stages of their treatments, this project aims to evaluate the association between depressive and/or anxious symptoms with (1) the post-operative morbimortality for EG cancer and (2) inflammation, immune and tumor markers.
We hypothesize that there is an association between anxious and/or depressive symptoms, post-operative morbimortality and disrupted immunological and inflammatory responses. The results will provide a better understanding of the role of affective symptoms in post-operative morbimortality and will contribute to its reduction by assessing and treating the affective symptoms at the early stages of treatment.
Funding: Ministry of Health, PHRIP
Principal investigator: Maryline BOURGOIN, chief of the Transversal Unit of Patient Education at the Teaching Hospital of Lille
Scientific Director : Sophie LELORAIN
Although patient education (PE) programmes have been proved very efficient to help patients regarding their quality of life, biological markers and medical complications, only between 10 to 60% of patients uptake such programmes. Our aim was to identify, drawing upon the Health Belief Model, patients’ beliefs regarding PE that will predict their participation in PE.
This prospective research took place in 8 departments of the University Hospital of Lille. Collected data on 450 patients are about to be analyzed.